Published in Computational Mechanics Vol. 54 (4), pp. 1013-1022, 2014
doi: 10.1007/s00466-014-1040-2


A reduced-order model for an efficient analysis of cardiovascular hemodynamics problems using multiscale approach is presented in this work. Starting from a patient-specific computational mesh obtained by medical imaging techniques, an analysis methodology based on a two-step automatic procedure is proposed. First a coupled 1D-3D Finite Element Simulation is performed and the results are used to adjust a reduced-order model of the 3D patient-specific area of interest. Then, this reduced-order model is coupled with the 1D model. In this way, three-dimensional effects are accounted for in the 1D model in a cost effective manner, allowing fast computation under different scenarios. The methodology proposed is validated using a patient-specific aortic coarctation model under rest and non-rest conditions.

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Published on 01/01/2014

DOI: 10.1007/s00466-014-1040-2
Licence: CC BY-NC-SA license

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