Published in Computer Methods in Biomechanics and Biomedical Engineering Vol. 18 (8), pp. 805-815, 2015
doi: 10.1080/10255842.2013.847095

Abstract

An aortic dissection (AD) is a serious condition defined by the splitting of the arterial wall, thus generating a secondary lumen [the false lumen (FL)]. Its management, treatment and follow-up are clinical challenges due to the progressive aortic dilatation and potentially severe complications during follow-up. It is well known that the direction and rate of dilatation of the artery wall depend on haemodynamic parameters such as the local velocity profiles, intra-luminal pressures and resultant wall stresses. These factors act on the FL and true lumen, triggering remodelling and clinical worsening. In this study, we aimed to validate a computational fluid dynamic (CFD) tool for the haemodynamic characterisation of chronic (type B) ADs. We validated the numerical results, for several dissection geometries, with experimental data obtained from a previous in vitro study performed on idealised dissected physical models. We found a good correlation between CFD simulations and experimental measurements as long as the tear size was large enough so that the effect of the wall compliance was negligible.

Back to Top

Document information

Published on 10/12/18
Submitted on 10/12/18

DOI: 10.1080/10255842.2013.847095
Licence: CC BY-NC-SA license

Document Score

0

Times cited: 6
Views 9
Recommendations 0

Share this document

claim authorship

Are you one of the authors of this document?