Design optimization has already become an important tool in industry. The benefits are clear, but several drawbacks are still present, being the main one the computational cost. The numerical simulation involved in the solution of each evaluation is usually costly, but time and computational resources are limited. Time is key in industry. The present communication focuses on the methodology applied to optimize the installation and design of a Tuned Mass Damper. It is a structural device installed within the tower of a wind turbine aimed to stabilize the oscillations and reduce the tensions and the fatigue loads. The paper describes the decision process to define the optimization problem, as well as the issues and solutions applied to deal with a huge computational cost.