Severe aortic insufficiency secondary to infective endocarditis in a patient with intraventricular septal defect, case report

Abstract

Background: infective endocarditis is a septic condition predominantly of bacterial origin, although there is a fungal etiology of the native valvular endothelium of the heart, it is a disease associated with high mortality and complications, despite advances in its approach, its incidence has not decreased in the last 30 years. Case presentation: 30-year-old black female patient, housewife, with a personal history of intraventricular septal defect. She went to the on-call department for presenting high fever at any time of the day accompanied by chills, with joint pain. She had undergone a curettage due to the presence of a fetal ovum. Three days prior to this, she had a fever of 38 degrees Celsius with no specific time of day, accompanied by chills, which was easily relieved with sodium metamizole. The fever persisted daily, which led to several hospital admissions, after which she was discharged home with no diagnostic cause. She was readmitted due to a chronic febrile syndrome, to which joint pain was added. Medulogram was performed and was not useful, suggesting iliac crest biopsy to rule out anarco-proliferative processes, and antimicrobials were not administered during this time. Conclusions: infective endocarditis on native valves with negative blood cultures remains a challenge, despite medical advances in recent decades, and due to demographic changes of patients and the disease, it remains a complex pathology with high morbidity and mortality.

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