To model reliably behavioral systems with complex bio-social interactions, accounting for uncertainty quantification, is critical for many application areas. However, in terms of the mathematical formulation of the corresponding problems, one of the major challenges is coming from the fact that corresponding stochastic processes should, in most cases, be considered in bounded domains, possibly with obstacles. This has been known for a long time and yet, very little has been done for the quantification of uncertainties in modelling complex behavioral systems described by such stochastic processes. In this paper, we address this challenge by considering a coupled system of Skorokhodtype stochastic differential equations (SDEs) describing interactions between active and passive participants of a mixed-population group. In developing a multi-fidelity modelling methodology for such behavioral systems, we combine lowand high-fidelity results obtained from (a) the solution of the underlying coupled system of SDEs and (b) simulations with a statistical-mechanics-based lattice gas model, where we employ a kinetic Monte Carlo procedure. Furthermore, we provide representative numerical examples of healthcare systems, subject to an epidemic, where the main focus in our considerations is given to an interacting particle system of asymptomatic and susceptible populations.
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