The two main lines of medical research in this project are vascular anatomy (large vessels around the heart, coronaries and peripheral arteries) and heart chambers. Geometric models will be constructed to aid clinical diagnosis or multiphysical modelling and simulation. Two levels of complexity will be considered. For heart modelling, the first level will concentrate on models of the left and right ventricular cavities for robust and efficient extraction of simple clinical indexes of geometry, volume, mass, and wall kinetics. The second level will aim at more complex, fourchambered models, which will be important in developing comprehensive solid and fluid models to assist the design of medical devices.