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| − | + | PHARMACOEPIDEMIOLOGY AND BIOINFORMATICS: EVOLUTION AND INTEGRATION OF ANALYTICAL WAYS ON PRECISION THERAPEUTICS ON CARDIOVASCULAR RISK | |
| − | + | ABSTRACT | |
| − | + | The pharmacological intervention is positioned as a common element in the process of approaching patients at different levels of care, with the aim of limiting the natural evolution of various pathological conditions, generating symptomatic relief, preventing and in some circumstances, diagnosing. The use of therapeutic molecules within the framework of clinical decisions requires the conjunction and analysis of elements such as pharmacological, regulatory, epidemiological knowledge and individual characterization of the patient. This complex and multivariable scenario implies an important effort of the health professional, who will also find himself with a systematic element in front of the exposure to drugs: the adverse drug reactions, unwanted and within the therapeutic spectrum. To support the professional in the area of health sciences, bioinformatics and biostatistical information analysis processes arise, techniques that together with the advance in omics sciences, allow to describe, generate inference, explain, predict and apply knowledge of the science of data, at the bedside of the patient. The incorporation of bioinformatics and pharmacological analysis in complex levels of health care, with special reference to cardiovascular drugs, would allow to anticipate problems derived from interactions, indications, use, compliance and clinical impact. | |
| − | + | Keywords: Cardiovascular drugs, database, computational biology, medical informatics, analytical epidemiology, pharmacogenomics | |
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Revision as of 18:16, 31 May 2019
PHARMACOEPIDEMIOLOGY AND BIOINFORMATICS: EVOLUTION AND INTEGRATION OF ANALYTICAL WAYS ON PRECISION THERAPEUTICS ON CARDIOVASCULAR RISK ABSTRACT The pharmacological intervention is positioned as a common element in the process of approaching patients at different levels of care, with the aim of limiting the natural evolution of various pathological conditions, generating symptomatic relief, preventing and in some circumstances, diagnosing. The use of therapeutic molecules within the framework of clinical decisions requires the conjunction and analysis of elements such as pharmacological, regulatory, epidemiological knowledge and individual characterization of the patient. This complex and multivariable scenario implies an important effort of the health professional, who will also find himself with a systematic element in front of the exposure to drugs: the adverse drug reactions, unwanted and within the therapeutic spectrum. To support the professional in the area of health sciences, bioinformatics and biostatistical information analysis processes arise, techniques that together with the advance in omics sciences, allow to describe, generate inference, explain, predict and apply knowledge of the science of data, at the bedside of the patient. The incorporation of bioinformatics and pharmacological analysis in complex levels of health care, with special reference to cardiovascular drugs, would allow to anticipate problems derived from interactions, indications, use, compliance and clinical impact. Keywords: Cardiovascular drugs, database, computational biology, medical informatics, analytical epidemiology, pharmacogenomics
2 The main text
3 Bibliography
4 Acknowledgments
5 References
Document information
Published on 02/06/19
Licence: CC BY-NC-SA license
