Scipediacontent: Scipediacontent moved page Draft Content 944221711 to Yoder-Himes et al 2011a

2021-02-02T03:36:40Z

Scipediacontent moved page Draft Content 944221711 to Yoder-Himes et al 2011a

Scipediacontent: Created page with " == Abstract == Closing of gaps in draft assemblies using Next Generation Sequencing (NGS) data is becoming increasingly important. In this paper we present CloG, a software..."

2021-02-02T03:36:34Z

Created page with " == Abstract == Closing of gaps in draft assemblies using Next Generation Sequencing (NGS) data is becoming increasingly important. In this paper we present CloG, a software..."

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== Abstract ==

Closing of gaps in draft assemblies using Next Generation Sequencing (NGS) data is becoming increasingly important. In this paper we present CloG, a software pipeline that uses NGS data to close gaps in draft assemblies. Firstly, CloG uses the VELVET assembler to generate a hybrid assembly from a mixture of reads: short reads from the NGS data and the original draft assembly (treated as long reads). It then closes gaps between adjacent contigs by reconciling (i.e., “stitching”) the two assemblies. By exploiting the strengths of both hybrid assembly and stitching reassembly, CloG is able to outperform its contemporaries in closing gaps in the draft assembly of the bacterium Burkholderia dolosa.

== Original document ==

The different versions of the original document can be found in:

* [http://users.cis.fiu.edu/~giri/papers/CloG_Yang.pdf http://users.cis.fiu.edu/~giri/papers/CloG_Yang.pdf]

* [http://users.cis.fiu.edu/~giri/papers/CloG_Yang.pdf http://users.cis.fiu.edu/~giri/papers/CloG_Yang.pdf],
: [https://users.cs.fiu.edu/~giri/papers/CloG_Yang.pdf https://users.cs.fiu.edu/~giri/papers/CloG_Yang.pdf],
: [http://yadda.icm.edu.pl/yadda/element/bwmeta1.element.ieee-000005729881 http://yadda.icm.edu.pl/yadda/element/bwmeta1.element.ieee-000005729881],
: [https://dblp.uni-trier.de/db/conf/iccabs/iccabs2011.html#YangMNYL11 https://dblp.uni-trier.de/db/conf/iccabs/iccabs2011.html#YangMNYL11],
: [https://academic.microsoft.com/#/detail/2125150644 https://academic.microsoft.com/#/detail/2125150644]

* [http://xplorestaging.ieee.org/ielx5/5724107/5729857/05729881.pdf?arnumber=5729881 http://xplorestaging.ieee.org/ielx5/5724107/5729857/05729881.pdf?arnumber=5729881],
: [http://dx.doi.org/10.1109/iccabs.2011.5729881 http://dx.doi.org/10.1109/iccabs.2011.5729881]

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Yoder-Himes et al 2011a - Revision history

Scipediacontent: Scipediacontent moved page Draft Content 944221711 to Yoder-Himes et al 2011a

Scipediacontent: Created page with " == Abstract == Closing of gaps in draft assemblies using Next Generation Sequencing (NGS) data is becoming increasingly important. In this paper we present CloG, a software..."