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		<id>https://www.scipedia.com/wd/index.php?action=history&amp;feed=atom&amp;title=Perez_2019a</id>
		<title>Perez 2019a - Revision history</title>
		<link rel="self" type="application/atom+xml" href="https://www.scipedia.com/wd/index.php?action=history&amp;feed=atom&amp;title=Perez_2019a"/>
		<link rel="alternate" type="text/html" href="https://www.scipedia.com/wd/index.php?title=Perez_2019a&amp;action=history"/>
		<updated>2026-04-18T04:27:27Z</updated>
		<subtitle>Revision history for this page on the wiki</subtitle>
		<generator>MediaWiki 1.27.0-wmf.10</generator>

	<entry>
		<id>https://www.scipedia.com/wd/index.php?title=Perez_2019a&amp;diff=143249&amp;oldid=prev</id>
		<title>Scipediacontent at 14:04, 23 September 2019</title>
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				<updated>2019-09-23T14:04:24Z</updated>
		
		<summary type="html">&lt;p&gt;&lt;/p&gt;
&lt;a href=&quot;https://www.scipedia.com/wd/index.php?title=Perez_2019a&amp;amp;diff=143249&amp;amp;oldid=133998&quot;&gt;Show changes&lt;/a&gt;</summary>
		<author><name>Scipediacontent</name></author>	</entry>

	<entry>
		<id>https://www.scipedia.com/wd/index.php?title=Perez_2019a&amp;diff=133998&amp;oldid=prev</id>
		<title>Juan-Manuel-Pérez-Agudelo at 02:27, 3 June 2019</title>
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				<updated>2019-06-03T02:27:58Z</updated>
		
		<summary type="html">&lt;p&gt;&lt;/p&gt;
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				&lt;td colspan='2' style=&quot;background-color: white; color:black; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan='2' style=&quot;background-color: white; color:black; text-align: center;&quot;&gt;Revision as of 02:27, 3 June 2019&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l92&quot; &gt;Line 92:&lt;/td&gt;
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&lt;tr&gt;&lt;td class='diff-marker'&gt;&amp;#160;&lt;/td&gt;&lt;td style=&quot;background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;You should ensure that all references are cited in the text and that the reference list. References should preferably refer to documents published in Scipedia. Unpublished results should not be included in the reference list, but can be mentioned in the text. The reference data must be updated once publication is ready. Complete bibliographic information for all cited references must be given following the standards in the field (IEEE and ISO 690 standards are recommended). If possible, a hyperlink to the referenced publication should be given. See examples for Scipedia’s articles [1], other publication articles [2], books [3], book chapter [4], conference proceedings [5], and online documents [6], shown in references section below. --&amp;gt;==&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt;&amp;#160;&lt;/td&gt;&lt;td style=&quot;background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;You should ensure that all references are cited in the text and that the reference list. References should preferably refer to documents published in Scipedia. Unpublished results should not be included in the reference list, but can be mentioned in the text. The reference data must be updated once publication is ready. Complete bibliographic information for all cited references must be given following the standards in the field (IEEE and ISO 690 standards are recommended). If possible, a hyperlink to the referenced publication should be given. See examples for Scipedia’s articles [1], other publication articles [2], books [3], book chapter [4], conference proceedings [5], and online documents [6], shown in references section below. --&amp;gt;==&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt;&amp;#160;&lt;/td&gt;&lt;td style=&quot;background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt;&amp;#160;&lt;/td&gt;&lt;td style=&quot;background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt;−&lt;/td&gt;&lt;td style=&quot;color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&lt;/del&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan=&quot;2&quot;&gt;&amp;#160;&lt;/td&gt;&lt;/tr&gt;
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&lt;tr&gt;&lt;td class='diff-marker'&gt;−&lt;/td&gt;&lt;td style=&quot;color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;==4 Acknowledgments&amp;lt;!-- Acknowledgments should be inserted at the end of the document, before the references section. --&amp;gt;==&lt;/del&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan=&quot;2&quot;&gt;&amp;#160;&lt;/td&gt;&lt;/tr&gt;
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&lt;tr&gt;&lt;td class='diff-marker'&gt;&amp;#160;&lt;/td&gt;&lt;td style=&quot;background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt;&amp;#160;&lt;/td&gt;&lt;td style=&quot;background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;/td&gt;&lt;/tr&gt;

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&lt;/table&gt;</summary>
		<author><name>Juan-Manuel-Pérez-Agudelo</name></author>	</entry>

	<entry>
		<id>https://www.scipedia.com/wd/index.php?title=Perez_2019a&amp;diff=133996&amp;oldid=prev</id>
		<title>Juan-Manuel-Pérez-Agudelo: Juan-Manuel-Pérez-Agudelo moved page Draft Perez 576845196 to Perez 2019a</title>
		<link rel="alternate" type="text/html" href="https://www.scipedia.com/wd/index.php?title=Perez_2019a&amp;diff=133996&amp;oldid=prev"/>
				<updated>2019-06-03T02:24:52Z</updated>
		
		<summary type="html">&lt;p&gt;Juan-Manuel-Pérez-Agudelo moved page &lt;a href=&quot;/public/Draft_Perez_576845196&quot; class=&quot;mw-redirect&quot; title=&quot;Draft Perez 576845196&quot;&gt;Draft Perez 576845196&lt;/a&gt; to &lt;a href=&quot;/public/Perez_2019a&quot; title=&quot;Perez 2019a&quot;&gt;Perez 2019a&lt;/a&gt;&lt;/p&gt;
&lt;table class=&quot;diff diff-contentalign-left&quot; data-mw=&quot;interface&quot;&gt;
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				&lt;td colspan='1' style=&quot;background-color: white; color:black; text-align: center;&quot;&gt;Revision as of 02:24, 3 June 2019&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan='2' style='text-align: center;' lang='en'&gt;&lt;div class=&quot;mw-diff-empty&quot;&gt;(No difference)&lt;/div&gt;
&lt;/td&gt;&lt;/tr&gt;&lt;/table&gt;</summary>
		<author><name>Juan-Manuel-Pérez-Agudelo</name></author>	</entry>

	<entry>
		<id>https://www.scipedia.com/wd/index.php?title=Perez_2019a&amp;diff=133943&amp;oldid=prev</id>
		<title>Juan-Manuel-Pérez-Agudelo at 16:25, 31 May 2019</title>
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				<updated>2019-05-31T16:25:41Z</updated>
		
		<summary type="html">&lt;p&gt;&lt;/p&gt;
&lt;a href=&quot;https://www.scipedia.com/wd/index.php?title=Perez_2019a&amp;amp;diff=133943&amp;amp;oldid=133942&quot;&gt;Show changes&lt;/a&gt;</summary>
		<author><name>Juan-Manuel-Pérez-Agudelo</name></author>	</entry>

	<entry>
		<id>https://www.scipedia.com/wd/index.php?title=Perez_2019a&amp;diff=133942&amp;oldid=prev</id>
		<title>Juan-Manuel-Pérez-Agudelo at 16:20, 31 May 2019</title>
		<link rel="alternate" type="text/html" href="https://www.scipedia.com/wd/index.php?title=Perez_2019a&amp;diff=133942&amp;oldid=prev"/>
				<updated>2019-05-31T16:20:13Z</updated>
		
		<summary type="html">&lt;p&gt;&lt;/p&gt;
&lt;a href=&quot;https://www.scipedia.com/wd/index.php?title=Perez_2019a&amp;amp;diff=133942&amp;amp;oldid=133941&quot;&gt;Show changes&lt;/a&gt;</summary>
		<author><name>Juan-Manuel-Pérez-Agudelo</name></author>	</entry>

	<entry>
		<id>https://www.scipedia.com/wd/index.php?title=Perez_2019a&amp;diff=133941&amp;oldid=prev</id>
		<title>Juan-Manuel-Pérez-Agudelo at 16:18, 31 May 2019</title>
		<link rel="alternate" type="text/html" href="https://www.scipedia.com/wd/index.php?title=Perez_2019a&amp;diff=133941&amp;oldid=prev"/>
				<updated>2019-05-31T16:18:16Z</updated>
		
		<summary type="html">&lt;p&gt;&lt;/p&gt;
&lt;table class=&quot;diff diff-contentalign-left&quot; data-mw=&quot;interface&quot;&gt;
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				&lt;td colspan='2' style=&quot;background-color: white; color:black; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan='2' style=&quot;background-color: white; color:black; text-align: center;&quot;&gt;Revision as of 16:18, 31 May 2019&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l1&quot; &gt;Line 1:&lt;/td&gt;
&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 1:&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt;&amp;#160;&lt;/td&gt;&lt;td style=&quot;background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;PHARMACOEPIDEMIOLOGY AND BIOINFORMATICS: EVOLUTION AND INTEGRATION OF ANALYTICAL WAYS ON PRECISION THERAPEUTICS ON CARDIOVASCULAR RISK&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt;&amp;#160;&lt;/td&gt;&lt;td style=&quot;background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;PHARMACOEPIDEMIOLOGY AND BIOINFORMATICS: EVOLUTION AND INTEGRATION OF ANALYTICAL WAYS ON PRECISION THERAPEUTICS ON CARDIOVASCULAR RISK&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot;&gt;&amp;#160;&lt;/td&gt;&lt;td class='diff-marker'&gt;+&lt;/td&gt;&lt;td style=&quot;color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt;&amp;#160;&lt;/td&gt;&lt;td style=&quot;background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;ABSTRACT&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt;&amp;#160;&lt;/td&gt;&lt;td style=&quot;background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;ABSTRACT&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot;&gt;&amp;#160;&lt;/td&gt;&lt;td class='diff-marker'&gt;+&lt;/td&gt;&lt;td style=&quot;color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt;&amp;#160;&lt;/td&gt;&lt;td style=&quot;background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;The pharmacological intervention is positioned as a common element in the process of approaching patients at different levels of care, with the aim of limiting the natural evolution of various pathological conditions, generating symptomatic relief, preventing and in some circumstances, diagnosing. The use of therapeutic molecules within the framework of clinical decisions requires the conjunction and analysis of elements such as pharmacological, regulatory, epidemiological knowledge and individual characterization of the patient. This complex and multivariable scenario implies an important effort of the health professional, who will also find himself with a systematic element in front of the exposure to drugs: the adverse drug reactions, unwanted and within the therapeutic spectrum. To support the professional in the area of health sciences, bioinformatics and biostatistical information analysis processes arise, techniques that together with the advance in omics sciences, allow to describe, generate inference, explain, predict and apply knowledge of the science of data, at the bedside of the patient. The incorporation of bioinformatics and pharmacological analysis in complex levels of health care, with special reference to cardiovascular drugs, would allow to anticipate problems derived from interactions, indications, use, compliance and clinical impact.&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt;&amp;#160;&lt;/td&gt;&lt;td style=&quot;background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;The pharmacological intervention is positioned as a common element in the process of approaching patients at different levels of care, with the aim of limiting the natural evolution of various pathological conditions, generating symptomatic relief, preventing and in some circumstances, diagnosing. The use of therapeutic molecules within the framework of clinical decisions requires the conjunction and analysis of elements such as pharmacological, regulatory, epidemiological knowledge and individual characterization of the patient. This complex and multivariable scenario implies an important effort of the health professional, who will also find himself with a systematic element in front of the exposure to drugs: the adverse drug reactions, unwanted and within the therapeutic spectrum. To support the professional in the area of health sciences, bioinformatics and biostatistical information analysis processes arise, techniques that together with the advance in omics sciences, allow to describe, generate inference, explain, predict and apply knowledge of the science of data, at the bedside of the patient. The incorporation of bioinformatics and pharmacological analysis in complex levels of health care, with special reference to cardiovascular drugs, would allow to anticipate problems derived from interactions, indications, use, compliance and clinical impact.&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot;&gt;&amp;#160;&lt;/td&gt;&lt;td class='diff-marker'&gt;+&lt;/td&gt;&lt;td style=&quot;color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt;&amp;#160;&lt;/td&gt;&lt;td style=&quot;background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;Keywords: Cardiovascular drugs, database, computational biology, medical informatics, analytical epidemiology, pharmacogenomics&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt;&amp;#160;&lt;/td&gt;&lt;td style=&quot;background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;Keywords: Cardiovascular drugs, database, computational biology, medical informatics, analytical epidemiology, pharmacogenomics&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt;&amp;#160;&lt;/td&gt;&lt;td style=&quot;background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt;&amp;#160;&lt;/td&gt;&lt;td style=&quot;background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;/td&gt;&lt;/tr&gt;

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		<author><name>Juan-Manuel-Pérez-Agudelo</name></author>	</entry>

	<entry>
		<id>https://www.scipedia.com/wd/index.php?title=Perez_2019a&amp;diff=133940&amp;oldid=prev</id>
		<title>Juan-Manuel-Pérez-Agudelo at 16:16, 31 May 2019</title>
		<link rel="alternate" type="text/html" href="https://www.scipedia.com/wd/index.php?title=Perez_2019a&amp;diff=133940&amp;oldid=prev"/>
				<updated>2019-05-31T16:16:59Z</updated>
		
		<summary type="html">&lt;p&gt;&lt;/p&gt;
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				&lt;td colspan='2' style=&quot;background-color: white; color:black; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan='2' style=&quot;background-color: white; color:black; text-align: center;&quot;&gt;Revision as of 16:16, 31 May 2019&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l1&quot; &gt;Line 1:&lt;/td&gt;
&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 1:&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt;−&lt;/td&gt;&lt;td style=&quot;color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;del class=&quot;diffchange diffchange-inline&quot;&gt;==1 Title&lt;/del&gt;, &lt;del class=&quot;diffchange diffchange-inline&quot;&gt;abstract and keywords&amp;lt;!-- Your document should start &lt;/del&gt;with &lt;del class=&quot;diffchange diffchange-inline&quot;&gt;a concise &lt;/del&gt;and &lt;del class=&quot;diffchange diffchange-inline&quot;&gt;informative title. Titles are often used &lt;/del&gt;in &lt;del class=&quot;diffchange diffchange-inline&quot;&gt;information-retrieval systems&lt;/del&gt;. &lt;del class=&quot;diffchange diffchange-inline&quot;&gt;Avoid abbreviations and formulae where possible. Capitalize &lt;/del&gt;the &lt;del class=&quot;diffchange diffchange-inline&quot;&gt;first word &lt;/del&gt;of the &lt;del class=&quot;diffchange diffchange-inline&quot;&gt;title.&lt;/del&gt;&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt;+&lt;/td&gt;&lt;td style=&quot;color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins class=&quot;diffchange diffchange-inline&quot;&gt;PHARMACOEPIDEMIOLOGY AND BIOINFORMATICS: EVOLUTION AND INTEGRATION OF ANALYTICAL WAYS ON PRECISION THERAPEUTICS ON CARDIOVASCULAR RISK&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt;−&lt;/td&gt;&lt;td style=&quot;color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&amp;#160;&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt;+&lt;/td&gt;&lt;td style=&quot;color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins class=&quot;diffchange diffchange-inline&quot;&gt;ABSTRACT&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt;−&lt;/td&gt;&lt;td style=&quot;color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;del class=&quot;diffchange diffchange-inline&quot;&gt;Provide a maximum &lt;/del&gt;of &lt;del class=&quot;diffchange diffchange-inline&quot;&gt;6 keywords&lt;/del&gt;, &lt;del class=&quot;diffchange diffchange-inline&quot;&gt;and avoiding general and plural terms and multiple concepts (avoid&lt;/del&gt;, &lt;del class=&quot;diffchange diffchange-inline&quot;&gt;for example, '&lt;/del&gt;and&lt;del class=&quot;diffchange diffchange-inline&quot;&gt;', '&lt;/del&gt;of&lt;del class=&quot;diffchange diffchange-inline&quot;&gt;')&lt;/del&gt;. &lt;del class=&quot;diffchange diffchange-inline&quot;&gt;Be sparing &lt;/del&gt;with &lt;del class=&quot;diffchange diffchange-inline&quot;&gt;abbreviations: only abbreviations firmly established &lt;/del&gt;in the &lt;del class=&quot;diffchange diffchange-inline&quot;&gt;field should be used. These keywords will be used for indexing purposes&lt;/del&gt;.&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt;+&lt;/td&gt;&lt;td style=&quot;color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins class=&quot;diffchange diffchange-inline&quot;&gt;The pharmacological intervention is positioned as a common element in the process of approaching patients at different levels of care&lt;/ins&gt;, with &lt;ins class=&quot;diffchange diffchange-inline&quot;&gt;the aim of limiting the natural evolution of various pathological conditions, generating symptomatic relief, preventing &lt;/ins&gt;and in &lt;ins class=&quot;diffchange diffchange-inline&quot;&gt;some circumstances, diagnosing&lt;/ins&gt;. &lt;ins class=&quot;diffchange diffchange-inline&quot;&gt;The use of therapeutic molecules within &lt;/ins&gt;the &lt;ins class=&quot;diffchange diffchange-inline&quot;&gt;framework &lt;/ins&gt;of &lt;ins class=&quot;diffchange diffchange-inline&quot;&gt;clinical decisions requires &lt;/ins&gt;the &lt;ins class=&quot;diffchange diffchange-inline&quot;&gt;conjunction and analysis &lt;/ins&gt;of &lt;ins class=&quot;diffchange diffchange-inline&quot;&gt;elements such as pharmacological&lt;/ins&gt;, &lt;ins class=&quot;diffchange diffchange-inline&quot;&gt;regulatory&lt;/ins&gt;, &lt;ins class=&quot;diffchange diffchange-inline&quot;&gt;epidemiological knowledge &lt;/ins&gt;and &lt;ins class=&quot;diffchange diffchange-inline&quot;&gt;individual characterization &lt;/ins&gt;of &lt;ins class=&quot;diffchange diffchange-inline&quot;&gt;the patient&lt;/ins&gt;. &lt;ins class=&quot;diffchange diffchange-inline&quot;&gt;This complex and multivariable scenario implies an important effort of the health professional, who will also find himself &lt;/ins&gt;with &lt;ins class=&quot;diffchange diffchange-inline&quot;&gt;a systematic element &lt;/ins&gt;in &lt;ins class=&quot;diffchange diffchange-inline&quot;&gt;front of &lt;/ins&gt;the &lt;ins class=&quot;diffchange diffchange-inline&quot;&gt;exposure to drugs: the adverse drug reactions, unwanted and within the therapeutic spectrum&lt;/ins&gt;. &lt;ins class=&quot;diffchange diffchange-inline&quot;&gt;To support &lt;/ins&gt;the &lt;ins class=&quot;diffchange diffchange-inline&quot;&gt;professional in &lt;/ins&gt;the &lt;ins class=&quot;diffchange diffchange-inline&quot;&gt;area of health sciences&lt;/ins&gt;, &lt;ins class=&quot;diffchange diffchange-inline&quot;&gt;bioinformatics and biostatistical information analysis processes arise, techniques that together with &lt;/ins&gt;the &lt;ins class=&quot;diffchange diffchange-inline&quot;&gt;advance in omics sciences, allow to describe, generate inference, explain&lt;/ins&gt;, &lt;ins class=&quot;diffchange diffchange-inline&quot;&gt;predict &lt;/ins&gt;and &lt;ins class=&quot;diffchange diffchange-inline&quot;&gt;apply knowledge of &lt;/ins&gt;the &lt;ins class=&quot;diffchange diffchange-inline&quot;&gt;science &lt;/ins&gt;of &lt;ins class=&quot;diffchange diffchange-inline&quot;&gt;data, at &lt;/ins&gt;the &lt;ins class=&quot;diffchange diffchange-inline&quot;&gt;bedside of &lt;/ins&gt;the &lt;ins class=&quot;diffchange diffchange-inline&quot;&gt;patient. The incorporation of bioinformatics and pharmacological analysis in complex levels of health care&lt;/ins&gt;, &lt;ins class=&quot;diffchange diffchange-inline&quot;&gt;with special reference &lt;/ins&gt;to &lt;ins class=&quot;diffchange diffchange-inline&quot;&gt;cardiovascular drugs&lt;/ins&gt;, &lt;ins class=&quot;diffchange diffchange-inline&quot;&gt;would allow to anticipate problems derived from interactions&lt;/ins&gt;, &lt;ins class=&quot;diffchange diffchange-inline&quot;&gt;indications&lt;/ins&gt;, &lt;ins class=&quot;diffchange diffchange-inline&quot;&gt;use&lt;/ins&gt;, &lt;ins class=&quot;diffchange diffchange-inline&quot;&gt;compliance and clinical impact&lt;/ins&gt;.&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt;−&lt;/td&gt;&lt;td style=&quot;color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&amp;#160;&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt;+&lt;/td&gt;&lt;td style=&quot;color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins class=&quot;diffchange diffchange-inline&quot;&gt;Keywords: Cardiovascular drugs, database, computational biology, medical informatics, analytical epidemiology, pharmacogenomics&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt;−&lt;/td&gt;&lt;td style=&quot;color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;del class=&quot;diffchange diffchange-inline&quot;&gt;An abstract is required for every document; it should succinctly summarize &lt;/del&gt;the &lt;del class=&quot;diffchange diffchange-inline&quot;&gt;reason for &lt;/del&gt;the &lt;del class=&quot;diffchange diffchange-inline&quot;&gt;work&lt;/del&gt;, the &lt;del class=&quot;diffchange diffchange-inline&quot;&gt;main findings&lt;/del&gt;, and the &lt;del class=&quot;diffchange diffchange-inline&quot;&gt;conclusions &lt;/del&gt;of the &lt;del class=&quot;diffchange diffchange-inline&quot;&gt;study. Abstract is often presented separately from &lt;/del&gt;the &lt;del class=&quot;diffchange diffchange-inline&quot;&gt;article&lt;/del&gt;, &lt;del class=&quot;diffchange diffchange-inline&quot;&gt;so it must be able &lt;/del&gt;to &lt;del class=&quot;diffchange diffchange-inline&quot;&gt;stand alone. For this reason&lt;/del&gt;, &lt;del class=&quot;diffchange diffchange-inline&quot;&gt;references and hyperlinks should be avoided. If references are essential&lt;/del&gt;, &lt;del class=&quot;diffchange diffchange-inline&quot;&gt;then cite the author(s) and year(s). Also&lt;/del&gt;, &lt;del class=&quot;diffchange diffchange-inline&quot;&gt;non-standard or uncommon abbreviations should be avoided&lt;/del&gt;, &lt;del class=&quot;diffchange diffchange-inline&quot;&gt;but if essential they must be defined at their first mention in the abstract itself&lt;/del&gt;. &lt;del class=&quot;diffchange diffchange-inline&quot;&gt;--&amp;gt;==&lt;/del&gt;&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt;+&lt;/td&gt;&lt;td style=&quot;color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt;−&lt;/td&gt;&lt;td style=&quot;color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&amp;#160;&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt;+&lt;/td&gt;&lt;td style=&quot;color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt;−&lt;/td&gt;&lt;td style=&quot;color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&amp;#160;&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt;+&lt;/td&gt;&lt;td style=&quot;color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt;−&lt;/td&gt;&lt;td style=&quot;color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&amp;#160;&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt;+&lt;/td&gt;&lt;td style=&quot;color:black; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt;&amp;#160;&lt;/td&gt;&lt;td style=&quot;background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt;&amp;#160;&lt;/td&gt;&lt;td style=&quot;background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class='diff-marker'&gt;&amp;#160;&lt;/td&gt;&lt;td style=&quot;background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;==2 The main text&amp;lt;!-- You can enter and format the text of this document by selecting the ‘Edit’ option in the menu at the top of this frame or next to the title of every section of the document. This will give access to the visual editor. Alternatively, you can edit the source of this document (Wiki markup format) by selecting the ‘Edit source’ option.&lt;/div&gt;&lt;/td&gt;&lt;td class='diff-marker'&gt;&amp;#160;&lt;/td&gt;&lt;td style=&quot;background-color: #f9f9f9; color: #333333; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #e6e6e6; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;==2 The main text&amp;lt;!-- You can enter and format the text of this document by selecting the ‘Edit’ option in the menu at the top of this frame or next to the title of every section of the document. This will give access to the visual editor. Alternatively, you can edit the source of this document (Wiki markup format) by selecting the ‘Edit source’ option.&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;

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&lt;/table&gt;</summary>
		<author><name>Juan-Manuel-Pérez-Agudelo</name></author>	</entry>

	<entry>
		<id>https://www.scipedia.com/wd/index.php?title=Perez_2019a&amp;diff=133939&amp;oldid=prev</id>
		<title>Juan-Manuel-Pérez-Agudelo: Created page with &quot;==1 Title, abstract and keywords&lt;!-- Your document should start with a concise and informative title. Titles are often used in information-retrieval systems. Avoid abbreviatio...&quot;</title>
		<link rel="alternate" type="text/html" href="https://www.scipedia.com/wd/index.php?title=Perez_2019a&amp;diff=133939&amp;oldid=prev"/>
				<updated>2019-05-31T16:07:10Z</updated>
		
		<summary type="html">&lt;p&gt;Created page with &amp;quot;==1 Title, abstract and keywords&amp;lt;!-- Your document should start with a concise and informative title. Titles are often used in information-retrieval systems. Avoid abbreviatio...&amp;quot;&lt;/p&gt;
&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;==1 Title, abstract and keywords&amp;lt;!-- Your document should start with a concise and informative title. Titles are often used in information-retrieval systems. Avoid abbreviations and formulae where possible. Capitalize the first word of the title.&lt;br /&gt;
&lt;br /&gt;
Provide a maximum of 6 keywords, and avoiding general and plural terms and multiple concepts (avoid, for example, 'and', 'of'). Be sparing with abbreviations: only abbreviations firmly established in the field should be used. These keywords will be used for indexing purposes.&lt;br /&gt;
&lt;br /&gt;
An abstract is required for every document; it should succinctly summarize the reason for the work, the main findings, and the conclusions of the study. Abstract is often presented separately from the article, so it must be able to stand alone. For this reason, references and hyperlinks should be avoided. If references are essential, then cite the author(s) and year(s). Also, non-standard or uncommon abbreviations should be avoided, but if essential they must be defined at their first mention in the abstract itself. --&amp;gt;==&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
==2 The main text&amp;lt;!-- You can enter and format the text of this document by selecting the ‘Edit’ option in the menu at the top of this frame or next to the title of every section of the document. This will give access to the visual editor. Alternatively, you can edit the source of this document (Wiki markup format) by selecting the ‘Edit source’ option.&lt;br /&gt;
&lt;br /&gt;
Most of the documents in Scipedia are written in English (write your manuscript in American or British English, but not a mixture of these). Anyhow, specific publications in other languages can be published in Scipedia. In any case, the documents published in other languages must have an abstract written in English.&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
2.1 Subsections&lt;br /&gt;
&lt;br /&gt;
Divide your article into clearly defined and numbered sections. Subsections should be numbered 1.1, 1.2, etc. and then 1.1.1, 1.1.2, ... Use this numbering also for internal cross-referencing: do not just refer to 'the text'. Any subsection may be given a brief heading. Capitalize the first word of the headings.&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
2.2 General guidelines&lt;br /&gt;
&lt;br /&gt;
Some general guidelines that should be followed in your manuscripts are:&lt;br /&gt;
&lt;br /&gt;
*  Avoid hyphenation at the end of a line.&lt;br /&gt;
&lt;br /&gt;
*  Symbols denoting vectors and matrices should be indicated in bold type. Scalar variable names should normally be expressed using italics.&lt;br /&gt;
&lt;br /&gt;
*  Use decimal points (not commas); use a space for thousands (10 000 and above).&lt;br /&gt;
&lt;br /&gt;
*  Follow internationally accepted rules and conventions. In particular use the international system of units (SI). If other quantities are mentioned, give their equivalent in SI.&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
2.3 Tables, figures, lists and equations&lt;br /&gt;
&lt;br /&gt;
Please insert tables as editable text and not as images. Tables should be placed next to the relevant text in the article. Number tables consecutively in accordance with their appearance in the text and place any table notes below the table body. Be sparing in the use of tables and ensure that the data presented in them do not duplicate results described elsewhere in the article.&lt;br /&gt;
&lt;br /&gt;
Graphics may be inserted directly in the document and positioned as they should appear in the final manuscript.&lt;br /&gt;
&lt;br /&gt;
Number the figures according to their sequence in the text. Ensure that each illustration has a caption. A caption should comprise a brief title. Keep text in the illustrations themselves to a minimum but explain all symbols and abbreviations used. Try to keep the resolution of the figures to a minimum of 300 dpi. If a finer resolution is required, the figure can be inserted as supplementary material&lt;br /&gt;
&lt;br /&gt;
For tabular summations that do not deserve to be presented as a table, lists are often used. Lists may be either numbered or bulleted. Below you see examples of both.&lt;br /&gt;
&lt;br /&gt;
1. The first entry in this list&lt;br /&gt;
&lt;br /&gt;
2. The second entry&lt;br /&gt;
&lt;br /&gt;
2.1. A subentry&lt;br /&gt;
&lt;br /&gt;
3. The last entry&lt;br /&gt;
&lt;br /&gt;
* A bulleted list item&lt;br /&gt;
&lt;br /&gt;
* Another one&lt;br /&gt;
&lt;br /&gt;
You may choose to number equations for easy referencing. In that case they must be numbered consecutively with Arabic numerals in parentheses on the right hand side of the page. Below is an example of formulae that should be referenced as eq. (1].&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
2.4 Supplementary material&lt;br /&gt;
&lt;br /&gt;
Supplementary material can be inserted to support and enhance your article. This includes video material, animation sequences, background datasets, computational models, sound clips and more. In order to ensure that your material is directly usable, please provide the files with a preferred maximum size of 50 MB. Please supply a concise and descriptive caption for each file. --&amp;gt;==&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
==3 Bibliography&amp;lt;!-- &lt;br /&gt;
Citations in text will follow a citation-sequence system (i.e. sources are numbered by order of reference so that the first reference cited in the document is [1], the second [2], and so on) with the number of the reference in square brackets. Once a source has been cited, the same number is used in all subsequent references. If the numbers are not in a continuous sequence, use commas (with no spaces) between numbers. If you have more than two numbers in a continuous sequence, use the first and last number of the sequence joined by a hyphen &lt;br /&gt;
&lt;br /&gt;
You should ensure that all references are cited in the text and that the reference list. References should preferably refer to documents published in Scipedia. Unpublished results should not be included in the reference list, but can be mentioned in the text. The reference data must be updated once publication is ready. Complete bibliographic information for all cited references must be given following the standards in the field (IEEE and ISO 690 standards are recommended). If possible, a hyperlink to the referenced publication should be given. See examples for Scipedia’s articles [1], other publication articles [2], books [3], book chapter [4], conference proceedings [5], and online documents [6], shown in references section below. --&amp;gt;==&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
==4 Acknowledgments&amp;lt;!-- Acknowledgments should be inserted at the end of the document, before the references section. --&amp;gt;==&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
==5 References&amp;lt;!--[1] Author, A. and Author, B. (Year) Title of the article. Title of the Publication. Article code. Available: http://www.scipedia.com/ucode.&lt;br /&gt;
&lt;br /&gt;
[2] Author, A. and Author, B. (Year) Title of the article. Title of the Publication. Volume number, first page-last page.&lt;br /&gt;
&lt;br /&gt;
[3] Author, C. (Year). Title of work: Subtitle (edition.). Volume(s). Place of publication: Publisher.&lt;br /&gt;
&lt;br /&gt;
[4] Author of Part, D. (Year). Title of chapter or part. In A. Editor &amp;amp; B. Editor (Eds.), Title: Subtitle of book (edition, inclusive page numbers). Place of publication: Publisher.&lt;br /&gt;
&lt;br /&gt;
[5] Author, E. (Year, Month date). Title of the article. In A. Editor, B. Editor, and C. Editor. Title of published proceedings. Paper presented at title of conference, Volume number, first page-last page. Place of publication.&lt;br /&gt;
&lt;br /&gt;
[6] Institution or author. Title of the document. Year. [Online] (Date consulted: day, month and year). Available: http://www.scipedia.com/document.pdf. &lt;br /&gt;
--&amp;gt;==&lt;/div&gt;</summary>
		<author><name>Juan-Manuel-Pérez-Agudelo</name></author>	</entry>

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