Scipediacontent: Scipediacontent moved page Draft Content 817781197 to Mammoliti et al 2019a

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Scipediacontent moved page Draft Content 817781197 to Mammoliti et al 2019a

Scipediacontent: Created page with " == Abstract == BSTRACTThe field of Pharmacogenomics presents great challenges for researchers that are willing to make their studies reproducible and sh..."

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Created page with " == Abstract == BSTRACT</jats:title><jats:p>The field of Pharmacogenomics presents great challenges for researchers that are willing to make their studies reproducible and sh..."

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== Abstract ==

BSTRACTThe field of Pharmacogenomics presents great challenges for researchers that are willing to make their studies reproducible and shareable. This is attributed to the generation of large volumes of high-throughput multimodal data, and the lack of standardized workflows that are robust, scalable, and flexible to perform large-scale analyses. To address this issue, we developed pharmacogenomic workflows in the Common Workflow Language to process two breast cancer datasets in a reproducible and transparent manner. Our pipelines combine both pharmacological and molecular profiles into a portable data object that can be used for future analyses in cancer research. Our data objects and workflows are shared on Harvard Dataverse and Code Ocean where they have been assigned a unique Digital Object Identifier, providing a level of data provenance and a persistent location to access and share our data with the community.

Document type: Preprint

== Full document ==
<pdf>Media:Draft_Content_817781197-beopen899-5961-document.pdf</pdf>

== Original document ==

The different versions of the original document can be found in:

* [http://dx.doi.org/10.1038/s41597-019-0174-7 http://dx.doi.org/10.1038/s41597-019-0174-7] under the license https://creativecommons.org/licenses/by

* [http://dx.doi.org/10.1101/614560 http://dx.doi.org/10.1101/614560] under the license https://creativecommons.org/licenses/by/4.0

* [http://europepmc.org/articles/PMC6722117 http://europepmc.org/articles/PMC6722117]

* [https://www.biorxiv.org/content/biorxiv/early/2019/04/29/614560.full.pdf https://www.biorxiv.org/content/biorxiv/early/2019/04/29/614560.full.pdf]

* [https://www.nature.com/articles/s41597-019-0174-7.pdf https://www.nature.com/articles/s41597-019-0174-7.pdf] under the license cc-by

* [http://link.springer.com/article/10.1038/s41597-019-0174-7 http://link.springer.com/article/10.1038/s41597-019-0174-7],
: [https://doaj.org/toc/2052-4463 https://doaj.org/toc/2052-4463] under the license cc-by

* [http://www.nature.com/articles/s41597-019-0174-7.pdf http://www.nature.com/articles/s41597-019-0174-7.pdf],
: [http://www.nature.com/articles/s41597-019-0174-7 http://www.nature.com/articles/s41597-019-0174-7],
: [http://dx.doi.org/10.1038/s41597-019-0174-7 http://dx.doi.org/10.1038/s41597-019-0174-7]

* [https://syndication.highwire.org/content/doi/10.1101/614560 https://syndication.highwire.org/content/doi/10.1101/614560],
: [http://dx.doi.org/10.1101/614560 http://dx.doi.org/10.1101/614560] under the license https://creativecommons.org/licenses/by/4.0

* [https://www.biorxiv.org/content/10.1101/614560v2 https://www.biorxiv.org/content/10.1101/614560v2],
: [https://www.biorxiv.org/content/biorxiv/early/2019/04/19/614560.full.pdf https://www.biorxiv.org/content/biorxiv/early/2019/04/19/614560.full.pdf],
: [https://academic.microsoft.com/#/detail/2938899814 https://academic.microsoft.com/#/detail/2938899814]

* [https://www.ncbi.nlm.nih.gov/pubmed/31481707 https://www.ncbi.nlm.nih.gov/pubmed/31481707],
: [http://ui.adsabs.harvard.edu/abs/2019NatSD...6..166M/abstract http://ui.adsabs.harvard.edu/abs/2019NatSD...6..166M/abstract],
: [https://www.nature.com/articles/s41597-019-0174-7.pdf https://www.nature.com/articles/s41597-019-0174-7.pdf],
: [https://www.nature.com/articles/s41597-019-0174-7?error=cookies_not_supported&code=1fa1f8bf-98a0-4f33-bebd-14ef53c35af9 https://www.nature.com/articles/s41597-019-0174-7?error=cookies_not_supported&code=1fa1f8bf-98a0-4f33-bebd-14ef53c35af9],
: [https://academic.microsoft.com/#/detail/2971384141 https://academic.microsoft.com/#/detail/2971384141]

DOIS: 10.1038/s41597-019-0174-7 10.1101/614560

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Scipediacontent: Scipediacontent moved page Draft Content 817781197 to Mammoliti et al 2019a

Scipediacontent: Created page with " == Abstract == BSTRACTThe field of Pharmacogenomics presents great challenges for researchers that are willing to make their studies reproducible and sh..."