https://www.scipedia.com/wd/index.php?action=history&feed=atom&title=Khoury_et_al_2021aKhoury et al 2021a - Revision history2026-06-10T10:28:02ZRevision history for this page on the wikiMediaWiki 1.27.0-wmf.10https://www.scipedia.com/wd/index.php?title=Khoury_et_al_2021a&diff=218852&oldid=prevScipediacontent: Scipediacontent moved page Draft Content 435637082 to Khoury et al 2021a2021-03-11T15:41:00Z<p>Scipediacontent moved page <a href="/public/Draft_Content_435637082" class="mw-redirect" title="Draft Content 435637082">Draft Content 435637082</a> to <a href="/public/Khoury_et_al_2021a" title="Khoury et al 2021a">Khoury et al 2021a</a></p>
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<td colspan='1' style="background-color: white; color:black; text-align: center;">Revision as of 15:41, 11 March 2021</td>
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</td></tr></table>Scipediacontenthttps://www.scipedia.com/wd/index.php?title=Khoury_et_al_2021a&diff=218851&oldid=prevScipediacontent: Created page with "== Abstract == The Localized Collocation Meshless Method (LCMM) is applied to the solution of a set of partial differential equations describing the diffusive transport of a..."2021-03-11T15:40:57Z<p>Created page with "== Abstract == The Localized Collocation Meshless Method (LCMM) is applied to the solution of a set of partial differential equations describing the diffusive transport of a..."</p>
<p><b>New page</b></p><div>== Abstract ==<br />
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The Localized Collocation Meshless Method (LCMM) is applied to the solution of a set of partial differential equations describing the diffusive transport of a dermally injected compound. This efficient and accurate numerical technique then provides the framework for the estimation of pharmacokinetic (PK) parameters by the comparison of two models, both containing information derived from experimental results, using the iterative Golden Section search algorithm. This comparison is quantified using a norm between the two solution spaces. While this method does provide an estimate of the effective-diffusion coefficient, it ultimately demonstrates that a simple, free-diffusion model is inadequate for quantifying the spatial and temporal distribution of a dermally-injected compound if elimination effects are not accounted for properly.<br />
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== Full document ==<br />
<pdf>Media:Draft_Content_435637082p761.pdf</pdf></div>Scipediacontent